肝硬变Child-Pugh肝功能分级与电解质紊乱的关系

Relationship between Child-Pugh Degree of Cirrhosis and Disorder of Electrolytes

目的:探讨不同肝功能状况肝硬变电解质紊乱特点。方法:对154例肝硬变患者进行Child-Pugh肝功能分级,血K^+、Na^+、Cl^-、Ca^(2+)检测由自动生化分析仪完成。结果:4种离子紊乱依次是:低Na^+>低C国^->低Ca^(2+)>低K^+;Child-Pugh肝功能分级与电解质紊乱有关:4种离子均数与A、B、C分级有关,其中Na^+、Cl^-变化具统计学意义(P<0.01),4种离子紊乱百分率、电解质紊乱病例数与A、B、C分级具显著性差异(P<0.05,P<0.01);离子紊乱模式以低Na^+最多见,部分低Na^+、低Cl^-呈直线相关。结论:肝硬变患者电解质紊乱随肝功能的Child-Pugh分级的增高而明显。

Aim: To explore the characteristics of electrolyte disorders in cirrhosis with different liver function. Methods: The liver functions in 154 cases with cirrhosis were classified by Child-Pugh score system. The liver functions and electrolytes were detected by autoanalysers. Results: The arrangement of electrolytes in the order of their abnormal rates was Na+ , Cl- , Ca2+ , K + . Low Na+ was the most frequent among the electrolyte disorders, following by low Cl- . low Ca2+ and low K+ successively. The Child-Pugh degree of patients was related to the mean values of 4 electrolytes, especially Na+ and Cl- (P<0. 01). The rates of electrolyte disorders in Child B and Child C patients were higher than those in Child A patients. A linear relationship was found between the low Na+ and Cl-. Conclusion: The Child-Pugh degree of cirrhosis was correlated with the disorders of electrolytes.