摘要
D-乳酸是众多手性物质的合成前体,广泛应用于化工、农业、食品、医药、环保等领域。近年来,随着基因工程理论的不断成熟发展,分子生物学技术在D-乳酸生产领域的应用也逐渐受到关注。介绍了利用基因工程技术改造D-乳酸生产菌株的研究现状,并对未来研究趋势进行了展望。
D-lactic acid, as an important synthetic precursor of many chiral compounds,is widely used in chemical industry, agriculture, food industry, medicine industry, environmental protection field, and so on. Recently, the application of molecular biotechnology in D-lactate production has attracted increasing attention with the development of genetic engineering technology. In this paper, the progress in the modification of D-lactate-producing strain by genetic engineering technology is summarized.and the nrosnects far research trends are made.
出处
《现代化工》
CAS
CSCD
北大核心
2010年第10期13-17,19,共6页
Modern Chemical Industry
关键词
D-乳酸
丙酮酸
基因工程
基因敲除
D-lactic acid
pyruvate
genetic engineering
gene knock out
