体外受精─胚胎移植治疗不孕症(附20周期分析)

The treatment of infertility on in vitro fertilization and embryo transfer

目的探讨体外受精－胚胎移植（InvitrofertilizationandembryoTransferIVF－ET）治疗不孕症的效果。方法对18例不孕症妇女实施20周期IVF－ET治疗。采用BuserelinFSH／HMG／HCG或FSH／HMG／HCG方案控制起排卵，B型超声为主监测卵泡发育；阴道超声引导下穿刺取卵；上游法处理精液，Earle’s平衡盐液进行体外受精及增养。Tom导管进行宫腔内胚胎移植。结果均每周期取卵6．7个，卵细胞回收率74％，受精率88％，卵裂率74％，获4例临床妊娠．1例生化妊娠，妊娠率25％。结论IVF－ET是治疗输卵性不孕最有效的方法。

objective To investigate the effect on an in vitro fertilization and embryo transfer intreatment of infertility. Methods Eighteen women(twenty Cycles) with infertility were enrolled in anIVF-ET program. Buserclin/FSH/HMG/HCG and FSH/HMG/HCG regimens for ovulation inductionwere used. Mornitoring methods was daily folicular ultrasonography. Accupunctures under viginal ul-trasonography for oocyte retrieval were performed. The swim-up method was used on specimen Collec-tion and Earle's Saline was used for culture. The embryo retrieval was performed with Tom tube. Re-sults An average of 6. 7 oocytes recovered for one case. The recovery, the fertilization and the dividingrate was 74%, 88% and 74%respectively- In eighteen women four clinical and one chemical pregnancyoccurred. Pregnance rate was 25%. Conclusion IVF-ET is the effective method to treat the fertility offallopian tube.