流动人口与常住人口中5岁以下儿童脊髓灰质炎免疫状况及抗体水平比较分析

Analysis of Polio Immunization Stabal and Antibody beef Between Floahng Children and Resident Children Under 5 Years Old

对郑州市金水区内１～５岁的流动儿童及同龄常住儿童的脊髓灰质炎（脊灰）免疫状况及抗体水平，进行随机抽查并分别做了分析评价．流动儿童中达到＞３次服苗的占８０％，常住儿童占９８％。采用脊灰中和抗体测定法测定流动儿童脊灰中和抗体，脊灰Ⅰ、Ⅱ、Ⅲ型抗体阳性率分别为９６％、９８％、９４％；３个型抗体几何平均滴度（ＧＭＴ）分别为Ⅰ型１：１１０，Ⅱ型１：２０２，Ⅲ型１：的常住儿脊灰中和抗体阳性率Ⅰ、Ⅱ、Ⅲ型均为１００％，３个型抗体ＧＭＴ分别为Ⅰ型１：２９８、Ⅱ型１：３７７、Ⅲ型１：２２９．结果提示两组儿童的抗体水平有差别。如何提高流动儿童的免疫接种率，是当今计划免疫工作所面临的一大难题．通过本次调查分析，为今后加强流动儿童的计划免疫管理提供了一定的依据。

A random sampling was carried out in both the floating children and the residentchildren under 5 years old at Jinshul district of Zhengzhou, Henan Province, to analyze theimmune stated and to compare the polio antibody level in these two groups. About 80% ofthe floating children and 98% of the. resident children had administered 3 doses of oral poliovaccine. With micro-nelltrali-zation test to polio alltibody, it showed that, in floating'Children, the antibody positive rates of polio Ⅰ Ⅱ Ⅲ were 96%, 98%, 94% and GMT were1.100, 1.202, 1.94 respectively, while that in resident children were 100%, 100%, 100%, and1:298, 1:377, 1:229 respectively. There were significant differences in the polio antibody levelof the two groups. The investigation also showed that there was a relatively regularless-dose-crowd in the floating children.