儿童症状性癫癎手术疗效及影响因素的分析

Surgical outcomes of pediatric symptomatic epilepsy and their influencing factors

目的了解儿童症状性癫癎手术疗效的影响因素。方法对从2004年10月至2008年9月经手术治疗的儿童症状性癫癎48例随访结果进行回顾性分析。结果 48例患儿中,43例获得随访,随访时间12～51个月,平均27.3月。患儿术后癫癎结果评价采用Engel标准,其中I级32例(74%),II级4例(9%),III级4例(9%),IV级3例(7%)。术前癫癎发作频率是癫癎手术预后的独立因素(P<0.05)。结论儿童症状性癫癎手术疗效良好,术前癫癎发作频次是影响手术预后的因素。

Objective To investigate the surgical outcomes of pediatric symptomatic epilepsy and the influencing factors for postoperative outcomes.Methods A cohort of 48 children with symptomatic epilepsy received surgical treatment from October 2004 to September 2008.The surgical outcomes were followed up.Results A 27.3 months （range 12-51 months） follow-up was performed in 43 cases.Engel classification for evaluating postoperative epileptic outcomes showed that class Ⅰ in 32 cases （74%）,class Ⅱin 4 cases （9%）,class Ⅲin 4 cases （9%） and class Ⅳ in 3 cases （7%）.Preoperative seizure frequency is an independent predictor of postoperative epileptic outcomes （P〈0.05）.Conclusions Operative treatment can lead to a favorable result in children with symptomatic epilepsy.Preoperative seizure frequency is an independent influencing factor for postoperative outcomes.