针灸治疗抑郁随机对照试验的临床文献系统评价

Meta-analysis of randomized controlled trials on acupuncture and moxibustion treating depression

目的对针灸治疗抑郁随机对照试验临床文献进行系统评价,为抑郁的针灸治疗提供循证医学证据。方法采用循证医学方法,利用Review Manage4.2.7软件对1989年1月至2009年9月发表的针灸治疗抑郁的随机对照试验文献调研,筛选出符合纳入标准的235个临床试验,采用描述性分析,对其进行系统评价。结果近年来,针灸治疗抑郁的研究已受到人们较多的关注,相关文献发表篇数呈逐年上升趋势,但研究质量普遍不高。结论重视和加强针灸综合疗法及抑郁状态的大样本研究,提高临床随机对照研究的质量,规范治疗时间,进行随访记录,探索出可行的针灸盲法是急待解决的问题。

Objective To assess and analyze the randomized controlled trials on acupuncture and moxibustion treating depression.Methods Relative clinical research literatures published from in January 1989 to 2009 in September were collected.A systematic assessment of two hundred and thirty five papers which conformed with the enrolled criteria was made with Review Manage4.2.7.Results In the recent years,the study of acupuncture treatment of depression had been paid more and more attention.The number of articles published showed an upward trend year by year,but the quality was generally not high.Conclusions Strengthening the study of comprehensive acupuncture treatment of depression and the randomization,large sample study and standardized treatment time,exploring feasible blind acupuncture are urgent to be resolved at present.