多发梗死性痴呆的临床、CT及体感诱发电位分析

ClinicalCT and shortlatency somatosensory evoked potentials analyses of patients with multiinfarct dementia

目的与方法：对４０例多发梗死性痴呆（ＭＩＤ）患者进行临床、ＣＴ及短潜伏期体感诱发电位（ＳＬＳＥＰ）分析。结果：高血压、卒中史为ＭＩＤ的重要危险因素。ＭＩＤ临床突出表现为智能障碍而局灶性神经系统症状、体征则较轻微。梗死灶多位于基底节区、额叶、颞叶，且双侧梗死较单侧梗死更多见。ＭＩＤ常有ＳＬＳＥＰ异常。结论：ＭＩＤ的发病机制及ＣＴ、ＳＬＳＥＰ检测在ＭＩＤ的诊断及其与Ａｌｚｈｅｉｍｅｒ型痴呆鉴别诊断中的价值。

Objective and mathods:BZClinical manifestationCT scan and shortlatency somatosensory evoked potential (SLSEP) recordings of patients with multiinfarct dementia(MID) were studied. Results: The results indicated that hypertension and history of stroke were very important risk factors for MID.The chief clinical manifestations of MID were disorders of intelligence,but the local neurological symptoms and signs were very slight.The infarcts usually located in basal ganglia,frontal lobes,temporal lobes and bilateral infarcts were more often than unilateral infarcts.SLSEP were frequently altered in patients with MID. Conclusion: The mechanism of MID and value of CTSLSEP in diagnosis of MID and differential diagnosis between MID and senile dementia of Alzheimer type were discussed with a review of pertinent literature.