肺癌患者血清免疫抑制酸性蛋白检测

DETECTION ON THE IMMUNOSUPPRESSIVE ACIDICPROTEIN IN PATIENTS WITH LUNG CANCER

目的研究肺癌与血清免疫抑制酸性蛋白的关系。方法采用单向免疫扩散法，检测６５例肺癌患者、１５例肺部良性疾病病例、３０例健康对照人群血清免疫抑制酸性蛋白。结果肺癌患者血清免疫抑制酸性蛋白均值明显高于健康人和肺部良性疾患病人（Ｐ＜０．０５）。不同病理组织类型的肺癌之间、不同临床分期的肺癌患者之间，血清免疫抑制酸性蛋白水平无明显区别。结论免疫抑制酸性蛋白可作为肺癌的一个肿瘤标志物。

Objective To study the relationhip between lung cancer and serum immunosuppressive acidic protein (IAP). Methods The Single radial immunodiffusion method was used to detect IAP in 65 cases of lung cancer,15 cases of benign lung diseases and 30 normal controls. Results The level of serum IAP in lung cancer patients was much higher than that in benign lung diseases and normal controls (P< 0.05). As to the level of serum IAP,there were no differences between different pathological types and between different clinical stages in lung cancer.5HZConclusion IAP can be used as a tumour marker for lung cancer.