氟康唑序贯疗法治疗白色念珠菌感染128例疗效观察

Clinical observation of the fluconazole sequential therapy with candida albicans infection

目的：观察氟康唑序贯疗法治疗白念珠菌感染的疗效及不良反应。方法：用氟康唑治疗白色念珠菌感染128例,首剂800m g静脉点滴,后1次/d 400m g静脉点滴7~14 d,改为1次/d 200m g口服,总疗程2~4周;口咽部感染配合用1∶5氟康唑溶液,每日涂擦口咽部3次,连用5~7d。结果：总有效率为90.6%,不良反应发生率为10.9%。结论：氟康唑序贯疗法治疗白色念珠菌感染疗效高,不良反应少。

Objective：To observe the treating effect and side effect of fluconazole sequential therapy in candida albicans infection.Methods：Fluconazole injections were administered in a daily dose of 400mg/7～14 days in Candida albicans infection,then fluconazole capsules were givens in a dose of 200 mg everyday.The total treating time was 2～4 weeks.The period of daubing the mouth and throat three times everyday with 1： 5 fluconazole solution was 5～7 days when the mouth and throat were infected.Results： The total effective rate was 90.6%.The incidence rate of side effects was 10.9%.Conclusion：Fluconazole Sequential Therapy is fit for candida albicans infection,it has higher curing rate,less side effects.