江苏省北部地区华支睾吸虫病流行现状调查

Investigation on epidemic status of clonorchiasis in Northern Jiangsu Province

目的了解江苏省华支睾吸虫病流行现状,为制定防治方案提供科学依据。方法选择金湖县、新沂市、泗阳县和灌云县作为调查点,每县选择2个监测村,采用ELISA法对居民进行血清学检查,对血清学阳性者及其家属采用改良加藤法进行粪检复查。采用压片镜检法检测中间宿主淡水鱼感染华支睾吸虫囊蚴情况。收集猫、犬和猪等保虫宿主粪便,进行病原学检查。同时开展流行因素调查及病例调查。结果血清学共检测2 174人,阳性226人,阳性率为14.59%。其中,男性阳性率为8.02%(78/973),女性阳性率为12.32%(148/1 201),两者差异有统计学意义(P<0.05);粪检986人,发现华支睾吸虫感染者8例,感染率为0.81%。检测淡水鱼5种共757条,华支睾吸虫囊蚴感染率为5.02%。检测猫、犬粪便53份,感染率为20.75%。结论江苏省北部地区属华支睾吸虫病低度流行区,存在潜在流行因素,防治的重点是进一步做好流行病学调查工作,并加强宣传教育。

Objective To understand the current epidemic status of clonorchiasis in Jiangsu Province so as to provide evidence for policy-making of disease control.MethodsEight villages,2 villages in each of 4 counties（Jinhu County,Xinyi County,Siyang County and Guanyun County） in Jiangsu Province were selected as the investigation sites.The serum tests for checking the antibody against Clonorchis sinensis in residents were carried out by using ELISA.The people with positive results in serum test and their family members were examined by Kato-Katz technique.The metacercariae in fish were detected by tissue smear microscopy.The feces samples of cats,dogs and pigs were collected and examined in lab.Meanwhile,the epidemic factors and cases were also surveyed.ResultsTotally 2 174 cases were tested by ELISA and 10.40% of them were positive.The positive rates were 8.02%（78/973） in male and 12.32%（148/1 201） in female,showing a significant difference（P0.05）.Totally 986 cases were examined by Kato-Katz technique,8 infection cases were found and the infection rate was 0.81%.A number of 757 fish in 5 species were surveyed and the infection rate was 5.02%.A number of 53 feces samples of dogs and cats were examined and the infection rate was 20.75%.ConclusionsThe prevalence of C.sinensis infection is low in Jiangsu Province and the key effective control measures are well epidemic survey and health education.