羊水板层小体检测在预测胎肺成熟度中的应用

The Clinical Application of the Lamellarbody Count of Amniotic Fluid to the Prediction to Fetal Pulmonary Maturity

目的 探讨羊水板层小体的数量检测在预测胎肺成熟度中的应用.方法 选择2005年12月至2009年3月本院产科不同孕周的妊娠糖尿病患者192例,抽取羊水标本,使用血细胞计数仪检测羊水中板层小体的数量,确定其与胎肺成熟度的关系.结果 192例孕妇不同孕周板层小体的数量在（3～236）×109/L之间,孕34～35、36～37、38～39周板层小体数量与孕32～33周板层小体数量分别进行比较,经t检验,差异有统计学意义（P＜0.05）;孕34～35、36～37、38～39周板层小体数最分别进行两两比较,经t检验,差异无统计学意义（P＞0.05）.在192例新生儿中有15例发生新生儿呼吸窘迫综合征（NRDS）,发病率为7.81%.结论 羊水板层小体检测是预测胎肺成熟度很好的初筛方法,简单易于操作,值得临床推广.

Objective To measure of the lamellarbody（LB） count in amniotic fluid in the prediction about fetal pulmonary maturation. Methods Select 192 in patients pregnant women at different weeks of gestation from 2005.12 to 2009.3 in Tianjin City Hospital for Gynaecology and Obsterics,extract amniotic fluid to detect lamellarbody Count by whole blood cells counter in order to kown the fetal pulmonary maturity. Results The lamellarbody count was varied from 3 to 236 5（ 109/L, To compare the lamellar body count in 32-33 gestational weeks with it in 34-35.36-37.38 39 gestational weeks,by t test,P〈0.05 there was statistic signifi cance; To compare the lamellarbody count in both 34 35.36 37.38-39 gestational weeks,by t test ,P〉0.05 there was no statistic significance. There were 15 neonatal respiratorydistress syndrome take place in 192 new borns, incidence of the disease was 7.81%. Conclusion The lamellarbody count is a good screen method in prediction about fetal pulmonary maturation,it is simple and quick operation and worth to clinical spreaded.