急性脑血管病患者血清超敏C反应蛋白和心肌酶变化分析

Analysis the Changes Hs-CRP and Myocardial Enzymes in Patients with Acute Cerebrovascular Disease

目的探讨急性脑血管病患者(脑出血、脑梗死)血清超敏C反应蛋白(hs-CRP)和心肌酶谱(AST、LDH、CK、CK-MB)含量变化及临床意义。方法对121例急性脑血管病患者和58例健康体检者进行血清hs-CRP和心肌酶谱水平的检测。结果脑出血组和脑梗死组血清中hs-CRP、心肌酶的水平明显高于健康对照组(P<0.01),脑出血组和脑梗死组之间比较差异无统计学意义(P>0.05),有意识障碍组和无意识障碍组比较差异有统计学意义(P<0.01)。结论急性脑血管病患者血清hs-CRP和心肌酶水平明显升高,其检测水平与疾病的性质无关,与病情严重程度一致,对这些指标的检测有助于判断病情的进展和预后。

Objective To discuss the changes and clinical significane of high sensitivity C reactive protein（hs-CRP）and myocardial enzymes（AST.LDH.CK.CK-MB）in patients with acute cerebrovaseular disease（cerebral hemorrhage.cerebral infarction）. Methods To dectect hs-CRP and myocardial enzymes in 121 patients with acute cerebrovascular disease and 58 healthy subjects. Results Compared with the control group, hs-CRP and myocardial enzymes in the patient group were significantly higher（P〈 0. 01） , there was no significant difference in hs-CRP and myocardial enzymes between the cerebral hemorrhage group and cerebral infarction group（P〉0.05）. There was a significant difference in hs-CRP and myocardial enzymes between the conscious disturbance group and the unconscious disturbance group（P〈0.01）. Conclusion There was a significant development in hs-CRP and my ocardial enzymes in patients with acute cerebrovascular disease. The concentration was not related to the character of diease, but it was consistent with the severity of diease. It will contribute to the development estimation and prognosis valuation for the acute ce- rebrovascular disease.