摘要
目的：对尖锐湿疣（ＣＡ）中的人乳头瘤病毒（ＨＰＶ）及人巨细胞病毒（ＨＣＭＶ）进行检测。方法：采用聚合酶链式反应（ＰＣＲ）。结果：新鲜湿疣中ＨＰＶ阳性率为８０．８％，其中ＨＰＶ１１／６ｂ（＋）者１９例，ＨＰＶ１６（＋）者２例。石蜡包埋组织中ＨＰＶ阳性率为５８．３％。５例ＨＰＶ强阳性的湿疣组织ＨＣＭＶ检测全部阴性。结论：新鲜组织的ＨＰＶ检出率高于石蜡包埋组织；部分湿疣由ＨＰＶ１６感染所致，应注意其恶变倾向；本文结果不支持ＣＡ中ＨＰＶ与ＨＣＭＶ复合感染的可能。
Objective:Human Papillomavirus(HPV)and Human cytomegalovirus(HCMV)were detcted in Condyloma acuminatum(CA)specimens.Methods:Polymerase chain reaction(PCR)method was used.Results:HPV positivity rate in fresh specimens was 80.8%(21/26);among the 21HPV(+)cases,HPV11/6b(+)and HPV16(+)were in 19 and 2 respectivedly.In paraffin embedded tissue,the positivity rate was 58.3%(7/12).HCMV was negative in five cases which was strong positive for HPV.Conclusion:the HPV detection rate in fresh specimens was higher than that in paraffin embedded tissue.There is a malignant tendency in parts of CA caused by HPV16 infection.Our results disagree about the possibility of complex infection from HPV and HCMV in CA.
出处
《承德医学院学报》
1999年第2期104-105,共2页
Journal of Chengde Medical University
关键词
尖锐湿疣
PCR
乳头瘤病毒
巨细胞病毒
石蜡包埋
Condyloma acuminatum
Polymerase chain reaction
Human Papillomavirus
Human cytomegalovirus
