不稳定型心绞痛与血胆红素的关系

Relationship between the level of serum bilirubin and unstable angina pectoris

目的:探讨血清胆红素水平与不稳定型心绞痛的关系。方法:心内科住院患者98例,经冠状动脉造影分成两组,冠心病(CHD)组65例,其中不稳定型心绞痛(UAP)组35例,稳定型心绞痛(SAP)组30例;非CHD组33例。均采用2,4-二氯苯胺重氮盐(DCA)比色法测定血清胆红素水平。结果:UAP组血清总胆红素(15.17±4.10)μmol/L、间接胆红素(11.31±3.12)μmol/L水平明显低于SAP组[(18.69±5.48)μmol/L,(14.27±4.06)μmol/L]和对照组[(17.86±3.53)μmol/L,(14.08±2.58)μmol/L,P<0.01],而SAP组与对照组相比无显著性差异(P>0.05)。结论:血清胆红素水平与不稳定型心绞痛有关,有可能成为评价不稳定型心绞痛患者的生化标志物。

Objective： To investigate the relationship between the level of serum bilirubln and unstable angina pectoris. Methods： A total of 98 patients who underwent coronary radiography were divided into coronary heart disease （CHD） group （65 eases） and normal control group （33 cases） . The CHD group was divided into stable angina pectoris （SAP） group （30 cases） and unstable angina pectoris （UAP） group （35 cases） . The level of serum bilirubin was measured by 2, 4--Dichloroaniline diazonium （DCA） colorimetry. Results： The serum total bilirubin level of patients with UAP was （15.17± 4.10）μmol/L and indirect bilirubin was （11.31± 3.12）μmol/L they were significantly lower than those of SAP group E （18.69 ±5.48）μmol/L. （14.27±4.06） μmol/L and normal control group [ （17.86±3.53）μmol/L, （14.08±2.58）μmol/L, P〈0. 011 . There was no significant difference between SAP group and normal control group （P〈0.05）. Conclusion： The level of serum bilirubin is related with unstable angina pectoris, and it will perhaps become a biochemical marker to assess whether patients with UAP.