住院2型糖尿病患者抑郁的患病率及危险因素调查

Investigation of the prevalence of depression and its risk factors in the resident type 2 diabetes patients

目的研究2型糖尿病患者抑郁的患病率,分析2型糖尿病合并抑郁危险因素。方法选取86例住院2型糖尿病患者,进行Zung氏抑郁自评量表(SDS)测评,根据SDS得分,计算出抑郁严重度指数,严重度指数≥0.5者为抑郁。以抑郁严重度指数为因变量(Y=0,1),分别以性别、年龄、文化程度、BMI、PG、PG2h、HbA1c、TG、CH、FIB、UAER、病程、并发症数目及有无使用胰岛素为自变量进行非条件Logistic回归分析抑郁的危险因素。结果 86例2型糖尿病患者中患抑郁40例。不同PG、HbA1c、病程、并发症数目、有无使用胰岛素组抑郁患病率差异有统计学意义(P<0.05)。不同病程组并发症数目差异有统计学意义(P<0.05)。进入单因素非条件Logistic回归方程的变量有PG、HbA1c、并发症数目及有无使用胰岛素。进入多因素非条件Logistic回归方程的变量有并发症数目和有无使用胰岛素。结论 2型糖尿病患者抑郁的患病率为46.5%。并发症数目和有无使用胰岛素是2型糖尿病合并抑郁的独立危险因素。2型糖尿病患者并发症数目与病程相关。

Objective To study the prevalence of depression in type 2 diabetes;and to analysis the risk factors in the resident type 2 diabetes patients with depression.Methods 86 patients of type 2 diabetes were condaced randomly（male 48,female 38）.The experimenters finished the assessment of the Zung＇s self-rating depression scale（SDS）by the special messengers＇ assisting.The index of the depression severity was calculated by the score of the Zung＇s self-rating depression scale.Depression was defined when the index of the depression severity was more than 0.5.We analysised the risk factors of depression by the unconditional Logistic regression equation,using the index of the depression severity（Y=0,1）as dependent variable and sex,age,the years of educated,duration,BMI,PG,PG2h,HbA1c,TG,CH,FIB,UAER,the number of chronic diabetic complications,weather or not injecting insulin as independent variable.Results 40 of 86 type 2 diabetes had depression.The contrast of the prevalence of depression in different groups of HbA1c,duration,the number of chronic diabetic complications,weather or not injecting insulin were significant（P0.05）.The number of chronic diabetic complications had significant contrast in different groups of duration（P0.05）.Variables went into the unconditional univariate Logistic regression equation included PG,HbA1c,the number of chronic diabetic complications,weather or not injecting insulin.Variables went into the unconditional multivariate Logistic regression equation included the number of chronic diabetic complications,weather or not injecting insulin.Conclusion The prevalence of depression in type 2 diabetes is 46.5%.The number of chronic diabetic complications,weather or not injecting insulin are independent risk factors of depression.The number of chronic diabetic complications is correlation with the duration of diabetes.