慢性乙肝患者肝纤维化检测的临床意义

Chronic hepatitis B patient liver fibrosis examination clinical significance

目的：探讨慢性乙型肝炎患者在治疗前后肝纤维化指标（HA、LN、PCⅢ、CⅣ）的变化及临床意义.方法：用放射免疫分析测定50例慢性乙型肝炎患者肝纤维化指标的含量,并与35例正常健康人作比较.结果：慢性乙肝患者治疗前血清透明质酸（HA）、层粘连蛋白（LN）、Ⅲ型前胶原（PCⅢ）及Ⅳ型胶原（CⅣ）水平均高于健康对照组,差异有统计学意义（P0.05）.结论：检测慢性乙型肝炎患者肝纤维化指标对观察病情和预后判定具有重要的临床价值.

Objective, Discusses the chronic second grade hepatitis patieni around the treatment the liver fibrosis target （HA, LN, PC Ⅲ C Ⅳ ） Change and clinical significance. Methods： Determines 50 example chronic second grade hepatitis patient liver fibrosis target with the emission immunity analysis the content,and makes the comparison with 35 example normal healthy people. Results：The chronic hepatitis B patient treats blood serum hyaluric acid （HA）, level adhesion protein （ LN）, Ⅲ Precollagen （PC Ⅲ ） And Ⅳ Collagen （CⅣ） The water is higher than the healthy control group equally,the difference has statistics significance （P〈0.05）;Treats the latter four target water average remarkable drop, although still was higher than the healthy control group＇s,but two groups of differences did not have statistics significance （P〉0.05）. Conclusion： Examines the chronic second grade hepatitis patient liver fibrosis target to observe the condition and the prognosis determination has the important clinical value.