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100例大鼠原位肝移植 被引量:3

ONE HUNDRRD ORTHOTOPIC LIVER TRANSPLANTATIONS IN RATS
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摘要 目的防止大鼠原位肝移植术后肝上下腔静脉吻合口撕裂出血,减少受体血管重建后吻合口远侧已形成血栓引起的肝坏死、下肢瘫痪和肺栓塞等严重并发症。方法参照Kamada介绍的方法,着重对肝上下腔静脉、门静脉和肝下下腔静脉吻合方法作了进一步改进。结果供肝热缺血时间2.5~3.5分钟,平均3.0分钟,安装袖套管时间约2.0分钟,肝上下腔静脉吻合时间平均为8.5分钟,供肝冷缺血时间23.0~30.5分钟,无肝期9.0~12.0分钟,1周存活率88%。结论改进的血管吻合方法提高了手术成功率。 Objective To prevent SHVC anastomotic site from laceration and decrease severe complications such as liver necrosis,hind limb paralysis and pulmonary embolism caused by thrombosis preformed at anastomotic stoma after recipient's vascular reconstruction. Methods Based on Kamada's method,we modified the anastomoses of suprahepatic vena cava,portal vein and infrahepaticvena cava. ResultsThe anhepatic period was 912 min,and the warm and cold ischemic time was 2.53.5 min and 23.030.5 min respectively.88% of the grafted animals survived for 1 week.Conclusion This led to an increased operation successful rate in orthotopic liver transplantation in the rat.
出处 《肝胆外科杂志》 1999年第3期225-226,共2页 Journal of Hepatobiliary Surgery
关键词 肝移植 模型 技术 Liver/transplantationRatModelTechneque
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  • 1张文海,中华器官移植杂志,1995年,1卷,12页

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  • 1张文海,有井滋樹,董雨亭,沈魁.大鼠原位肝移植术并发症的预防[J].中华器官移植杂志,1995,16(1):12-14. 被引量:14
  • 2严以群,杨甲梅,王轩,康俊升,陈汉,吴孟超.大鼠减体积性肝移植模型的初步研究[J].中华器官移植杂志,1996,17(2):55-57. 被引量:11
  • 3胡浩,肝胆外科杂志,1999年,7卷,225页
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