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肝脏注射醋酸引起局部坏死的实验研究 被引量:6

THE EXPERIMENT STUDY OF INTERHEPATIC INJECTION OF ACETIC ACID RESULTING IN LOCAL NECROSIS
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摘要 本实验的目的是证实醋酸可引起肝局部坏死,并且作用强于无水乙醇。对鼠肝局部注射醋酸后,从大体及组织学改变观察局部坏死情况并寻找最适浓度。结果发现醋酸可引起注射局部坏死完全,与周围分界非常清晰,其中50%醋酸引起的坏死区平均直径最大,且明显优于无水乙醇。提示醋酸可以作为一种制剂,用于局部注射治疗肝癌。 Objective:To confirm acetic acid injection can cause local necrosis of liver and its effect beyond absolute ethanol. Methods: after percutaneous acetic acid injection, the effect of coagulation necrosis in the liver of rats was detected by pathology. Results: necrosis occurred around the injection site of difference concentration of acetic acid into the liver. The mean diameter of the nerotic area caused by 50% acetic and is the largest and statistically significantly larger than that caused by absolute ethanol. Conclusion:Acetic acid may be proved to be an effective material for treating small hepatocellular carcinoma
出处 《上海生物医学工程》 1999年第2期46-48,共3页 Shanghai Journal of Biomedical Engineering
关键词 醋酸 肝坏死 肝癌 治疗 Acetic acid Absolute ethanol Hepatic local necrosis
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