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重症监护病房产AmpC酶大肠埃希菌的检测及耐药特性研究 被引量:2

Intensive Care Unit of Escherichia Coli Detection of AmpC and Resistance Characteristics
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摘要 目的探讨我院重症监护病房中大肠埃希菌产AmpC酶的情况及耐药特性。方法采用头孢西丁三相试验检测大肠埃希菌的产AmpC酶情况,采用纸片扩散法做药敏试验。结果重症监护病房分离的大肠埃希菌产AmpC酶情况比较严重,达到30.8%,耐药情况比较严峻。结论对于重症监护病房分离的大肠埃希菌多数为多重耐药菌株,对产AmpC酶株的大肠埃希菌临床经验用药应首选碳青酶烯类抗生素。 Objective To investigate the hospital in intensive care unit of Escherichia coli producing AmpC enzyme and antibiotic properties.Methods Three-phase test for detection of Escherichia coli cefoxitin AmpC enzyme production conditions,using disc diffusion method for drug susceptibility testing.Results Intensive care unit producing AmpC enzyme of Escherichia coli isolated situation more serious,reaching 30.8%,drug resistance is fairly severe.Conclusion Escherichia coli isolated in intensive care unit,most of multi-drug resistance strain of Escherichia coli strains producing AmpC enzyme of clinical experience in drug should be preferred Carbapenems antibiotic.
作者 张文斌
出处 《实用心脑肺血管病杂志》 2010年第11期1565-1566,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 AMPC酶 重症监护病房 大肠埃希菌 耐药 AmpC enzyme Intensive care unit Escherichia coli Resistance
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