摘要
目的了解2008年1月—2009年12月我院分离的铜绿假单胞菌分布及其耐药情况,以指导临床合理用药。方法收集临床分离的铜绿假单胞菌,利用法国梅里埃VITEK-2compat全自动细菌分析仪鉴定并对临床常用15种抗菌药物的耐药性进行分析。结果铜绿假单胞菌主要分离于痰液中以呼吸道感染为主,主要分布呼吸科、心血管内科、ICU病房,对氨苄西林、头孢替坦、头孢唑啉、氨苄西林/舒巴坦、复方新诺明5种药物的耐药率几近100%,亚胺培南、哌拉西林/他唑巴坦、耐药率均为25%。结论铜绿假单胞菌易产生多重耐药,加强耐药性监测,依据药敏结果合理选用有效的抗菌药物,控制院内感染。
Objective January 2008~ December2009 Pseudomonas aeruginosa hospital distribution and drug resistance to clinical therapy.Methods Pseudomonas aeruginosa clinical isolates,using the French Merieux VITEK-2compat Automatic identification of bacterial analyzer and 15 kinds of commonly used clinical resistance to antibiotics were analyzed.Results Pseudomonas aeruginosa isolated in sputum in the main to the main respiratory tract infection,mainly respiratory,cardiovascular medicine,ICU ward,ampicillin,cefotetan,cefazolin,ampicillin /sulbactam,cotrimoxazole drug resistance rate of 5 nearly 100%,imipenem,piperacillin /tazobactam,resistance rates were 25%.Conclusion Pseudomonas aeruginosa is easy to produce multi-drug resistance,Resistance surveillance,based on susceptibility of rational use of effective antibiotics to control nosocomial infections.
出处
《实用心脑肺血管病杂志》
2010年第11期1610-1611,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
铜绿假单胞菌
标本分布
耐药性
Pseudomonas aeruginosa
Sample distribution
Drug resistance