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诺和锐30治疗口服降糖药效果欠佳2型糖尿病患者的临床观察

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摘要 诺和锐30是一种双时相的胰岛素类似物,具有起效讯速、达到峰值早,作用持续时间较长的特点,很好的模拟了人体胰岛素的生理分泌.
作者 沈诤
机构地区 桐乡市第一人民医院中医科
出处 《全科医学临床与教育》 2010年第5期544-545,共2页 Clinical Education of General Practice
关键词 诺和锐30 2型糖尿病 临床观察 胰岛素类似物 患者 药效 降糖 口服
分类号 R587.1 [医药卫生—内分泌]
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  • 1Bretzel R G, Arnolds S, Medding J, et al. A direct efficacy and safety comparison of insulin aspart, human soluble insulin, and human premix insulin (70/30) in patients with type 2 diabetes[J]. Diabetes Care. 2004, 27(5): 1023-1027.
  • 2Raskin P, Guthne R A, Leiter L, et al. Use of insulin aspart: a fast-acting insulin analogue, as the mealtime insulin in the management of patients with type 1 diabetes[J]. Diabetes Care, 2000, 23(5): 583-588.
  • 3Christiansen J S, Vaz J A, Metelko Z, et al . Twice daily biphasic insulin aspart improves postprandial glycaemic control more effectively than twice daily NPH insulin, with low risk of hypoglycaemia, in patients with type 2 diabetes[J]. Diabetes Obes Metab, 2003, 5(6): 446-454.
  • 4Tamas G, Marre M, Astorga R, et al. Glycaemic control in type 1 diabetic patients using optimised insulin aspart or human insulin in a randomised multinational study[J]. Diabetes Res Clin Pract, 2001, 54(2): 105-114.
  • 5Bretzel R G, Medding J, Hirschberger S, et al. Insulin aspart efficacy and safety compared to human soluble insulin and human premix insulin (30/70) in patients with type 2 diabetes mellitus[J]. Diabetologia, 2001, 44 (Suppl 1): A209.
  • 6Danne T, Aman J, Schober E, et al. A comparison of postprandial and preprandial administration of insulin aspart in children and adolescents with type 1 diabetes[J]. Diabetes Care, 2003, 26(8): 2359-2364.
  • 7Bode B W, Strange P. Efficacy safety and pump compatibility of insulin aspart used in continuous subcutaneous insulin infusion therapy in patients with type 1 diabetes[J]. Diabetes Care, 2001, 24(1): 69-72.
  • 8Kvapil M, Mikolajczyk-Swatko A, Ostergaard A H, et al. Biphasic insulin aspart 30 combined with metformin provides better glycemic control in poorly controlled type 2 diabetic patients[J]. Diabetes, 2002, 51 (Suppl 2): A104.
  • 9McSorley P T, Bell P M, Jacobsen L V, et al. Twice-daily biphasic insulin aspart 30 versus biphasic human insulin 30: a double-blind crossover study in adults with type 2 diabetes mellitus[J]. Clin Ther, 2002, 24(4): 530-539.
  • 10Heller S R, Colagiuri S, Vaaler S, et al Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with Type 1 diabetes[J]. Diabet Med, 2004, 21(7): 769-775.

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全科医学临床与教育
2010年 第5期

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