摘要
目的：探讨乳腺癌骨转移的相关因素及处理对策。方法：本文对１９５４年１月～１９７７年１２月我院收治的２８０３例原发乳腺癌术后发生骨转移的１４５例患者临床资料进行回顾性分析。结果：乳腺癌术后骨转移发生率５．１％，骨转移部位分布较广泛，多数出现在脊柱，术后前５年发生率占７６．４％，腋淋巴结阳性患者较阴性患者较早发生转移。出现转移后经治疗患者较未治疗患者生存期有显著性差异。结论：乳腺癌术后骨转移出现时间与其分布有其规律，综合治疗后乳腺癌患者可延缓出现转移的时间。出现骨转移后，积极治疗，可达到延长生存期改善生存质量的目的。
Objective: To evaluated the related factor and treatment of bone matastases of breast cancer.
Methods:From January 1954 to December 1977,145 cases of bone metastasis of breast cancer
were retrospective studied. Results: The rate of bone matastasis was 5.1%(145/2803),vertebrae
tend to be the commonest sites for metastasis.76.4% patients with bone metastasis occurrence
in first five years.Bone metastasis was related to various poor prognostic factor:Spread to
lymph nodes and stage. The survival time of the patients with the treatment was significantly
higher than that without treatment. Conclusions: Systemic treatment can deley the occurrence of
bone metastasis and can also prolong the survival after the occurrence of bone metastasis.
关键词
乳腺癌
骨转移瘤
临床病理
breast cancer
bone metastasis
treatment
