低浓度甲磺酸罗哌卡因用于前列腺汽化电切术术后镇痛的临床观察

The observation of postoprative analgesia of low concentration of ropivacaine mesylate used in TUVP

目的比较甲磺酸罗哌卡因与布比卡因分别复合芬太尼用于前列腺汽化电切术术后硬膜外自控镇痛(PCEA)的临床效果及不良反应。方法选择40例择期行前列腺汽化电切手术的患者,腰硬复合麻醉,术后随机分为2组,Ⅰ组(n=20):0.125%甲磺酸罗哌卡因;Ⅱ组(n=20):0.125%布比卡因。2组均复合芬太尼2μg/kg。观察2组患者术后48h内的生命体征、出血量、镇痛效果及不良反应发生率。结果 2组患者生命体征、出血量、WHO疼痛分级、PCEA总用药量及有效按压次数比较差异均无统计学意义(P>0.05);恶心呕吐、头晕、皮肤瘙痒、低血压发生率组间差异也无统计学意义(P>0.05)。结论 0.125%甲磺酸罗哌卡因用于术后镇痛疗效可靠,无明显不良反应,值得临床推广应用。

Objective To compare effect and adverse reaction of ropivacaine mesylate,bupivacaine respectively combined with fentanyl on postoprative Patient-controlled epidural analgesia（PCEA） in TUVP.Methods 40 cases patients scheduled for transurethral vaporization of prostate surgery were randomly divided into 2 groups,Ⅰ组（n = 20）：0.125% ropivacaine mesylate;Ⅱ组（n = 20）：0.125% bupivacaine.2 groups were combined with fentanyl 2μg/kg.Observed vital signs,blood loss,analgesic effect and rate of adverse reaction of 2 groups.Results Vital signs,blood loss,WHO classification of pain,PCEA and effective compression of the total dosage of 2 groups were no significant difference（P 0.05）;The rate of nausea and vomiting,dizziness,skin itching,low blood pressure of two groups were no statistically significant differences（P 0.05） .Conclusion 0.125% ropivacaine mesylate has reliable efficacy for postoperative analgesia,without significant adverse reaction,is worthy of clinical application.