通心络胶囊治疗椎基底动脉供血不足98例临床疗效观察

Evaluation of the therapeutic effects on tongxinluo capsule in 98 patients with vertebral and basilar arterial blood supply insufficiency.

目的观察通心络胶囊治疗椎基底动脉供血不足的临床疗效。方法将188例椎基底动脉供血不足患者随机分为治疗组和对照组,治疗组口服通心络胶囊,对照组口服复方丹参片,均连续治疗8周,治疗前和治疗8周后予评分,并做经颅多普勒超声和血液流变学检查。结果治疗组降低血粘度、增加椎动脉和基底动脉平均血流速度均较对照组明显,P<0.05;治疗组改善临床症状的总有效率为94.9%,对照组为80%,前者明显高于后者,P<0.05。结论通心络胶囊对椎基底动脉供血不足具有良好的治疗作用。

Objective To evaluate the therapeutic effects on tongxinluo capsule in patients with vertebral and basilar arterial blood supply insufficiency.Methods 188 patients suffering with vertebral and basilar arterial blood supply insufficiency were randomly divided into treatment group and control group.These patients in treatment group were treated with tougxinluo capsule,and those in control group were given with fufang danshen.The therapeutic period were 8 weeks.Their symptoms marks,plasma adhesion and VM between vertebral basilar artery were recorded and checked respectively before treatment and after 8 weeks treatment.Results The effects of decreasing of plasma adhesion and increasing of VM between vertebral basilar artery in treatment group were significant than those in control group.The total efficiency of improving symptom was 94.9% in treatment group and 80% in control group.Conclusion Tongxinluo capsule has better therapeutic effects in patients with vertebral and basilar arterial blood supply insufficiency.