液基细胞学检测和TBS分类在宫颈病变筛查中的应用

Application of liquid-based cytology test and TBS cytology subdivision in the detection of cervical cancer

目的对液基细胞学检测和TBS分类法在宫颈病变筛查中的应用价值进行综合评价。方法采用液基细胞学检测宫颈细胞并进行TBS分类诊断,将诊断意义不明的不典型鳞状细胞(ASCUS)以上病变均列为阳性病例,且在阴道镜下活检,将细胞学检测结果与活检结果作对比分析。结果液基细胞学检测法标本满意率为94%,1980例受检者涂片中阳性病例为78例,阳性率为3.94%(78/1980),对78例细胞学检测异常者行阴道镜下活检与组织病理学诊断符合率为80.8%(63/78)。结论液基细胞学检测应用于宫颈细胞涂片筛查,明显提高了涂片的满意率和异常细胞检出率。TBS报告方式内容直观、易懂、具体。液基细胞学检查异常的病例配合阴道镜病理组织学活检,能及早发现宫颈早期病变,对防治宫颈癌发生起重要作用。

Objective To study the value of liquid-based cytology test （LCT）and Bethesda （TBS） cytology subdivision in the detection of cervical cancer. Methods A total of 1980 cases were detected using LCT and TBS. The samples of atypical squamous cell and more abnormal cell were positive,then the results were compared with those of colposopical biopsy examination. Results The satisfactory rate of LCT smears was 94%,78 samples were positive,and the positive rate was 3.94% （78/1980）. Of these 78 cases,63 cases was coincidental with the pathological examination,and the rate of agreement was 80.8% （63/78）.Conclusion If combined with colposcopical and pathological examination,LCT could find out the early cervical lesions as soon as possible. TBS cytology subdivision is more detailed,simple and direct. It is the key to prophylaxis and treatment of cervical cancer.