综合救治有机磷农药中毒合并呼吸衰竭临床分析

Clinical analysis of comprehensive treatment for acute organophosphorus pesticide poisoning combined with respiratory failure

目的探讨急性有机磷农药中毒(AOPP)合并呼吸衰竭的原因及有效救治措施。方法对45例AOPP合并呼吸衰竭患者的临床资料进行回顾性分析。运用洗胃、导泻、静脉注射阿托品、胆碱酯酶复能剂、机械通气等办法救治患者,观察AOPP合并呼吸衰竭的抢救成功率及死亡率。结果 AOPP伴呼吸衰竭患者45例,治愈37例,死亡8例,抢救成功率为82.2%,死亡率17.8%.结论及时彻底洗胃、合理应用阿托品及胆碱酯酶复能剂、适时气管插管及机械通气等综合救治措施是成功抢救AOPP合并呼吸衰竭的关键。

Objective To discuss the reason and effective rescue measure of acute organophosphorus pesticide poisoning combined with respiratory failure. Methods Clinical data of 45 cases of acute organophosphorus pesticide poisoning combined with respiratory failure were analyzed retrospectively. Gastrolavage,catharsis,injection of atropine intravenously,cholinesterase reactivators,and mechanical ventilation were used to cure the patients,and the successful rescue rate and death rate were calculated. Results Of the 45 cases,37 were cured,8 died,the successful rescue rate was 82.2%,and the death rate was 17.8%. Conclusion The key to rescue acute organophosphorus pesticide poisoning combined with respiratory failure successfully is comprehensive treatment and cure measures such as complete gastrolavage in time,the rational application of atropine and cholinesterase reactivators,timely tracheal intubation and mechanical ventilation and so on.