上海市北蔡镇老年人骨质疏松危险因素分析

Risk factor analysis for osteoporosis in aged people in Beicai Town of Shanghai

目的 探讨上海市北蔡地区老年人骨质疏松的危险因素,为骨质疏松的预防提供依据.方法 随机抽取上海市北蔡镇3个居委会1个行政村共608名60～79岁的老年人进行骨密度测定,同时进行问卷调查,使用美国GE公司的Lunar Prodigy Advance PA＋300164型双能X线骨密度仪对老年人正位腰椎和左股骨近端进行骨密度测定.结果男性骨质疏松率23%,女性61%;60～64岁、65～69岁、70～74岁、75～79岁4组骨质疏松率分别为40%、44%、53%、66%;体力劳动组骨质疏松率52%,非体力劳动组骨质疏松率42%;25岁时低体质量组、正常体质量组和超重组骨质疏松症率分别为56%、41%、58%;男性现体质量＜60 kg、60～70 kg、70～80 kg、＞80 kg 4组骨质疏松率分别为54%、19%、15%、23%;女性现体质量＜50 kg、50～60 kg、60～70 kg、＞70 kg 4组骨质疏松率分别为76%、67%、63%、30%;现体质指数BMI正常体质量组和超质量组骨质疏松率分别为61%、43%;无骨折史、1次骨折史、2次及以上骨折史三组骨质疏松率分别为41%、67%、74%;有生母驼背史和无生母驼背史组骨质疏松率分别为60%、47%.Logistic回归模型多因素分析显示：性别、年龄、骨折史、生母驼背史及内分泌和代谢性疾病史与骨质疏松发病关系密切,且有统计学意义（P＜0.05）.结论 上海市北蔡镇老年人骨质疏松与多种因素有关,尤其是高龄女性,患有内分泌和代谢性疾病,既往有骨折史及生母有驼背史者应注意防治.

Objective To investigate the risk factors for osteoporosis （OP） in aged people at Beicai Town in Shanghai, to provide proofs for preventing OP. Methods Questionnaire survey was carried out on bone density in 608 aged people （aged from 60 to 79 years） who were randomly chosen from 4 resident committees of Beicai Town in Shanghai. Everyone underwent bone mineral density （BMD） assay of lumbar spine and total hip by DEXA machine. Results The rate of OP was 23 % in male group, and 61% in female group. It was 40% in 60-64 years old group, 44% in 65-69 years old group, 53% in 70-74 years old group and 66% in 75-79 years old group. The rate of OP was 52% in manual work group, and 42 % in non-manual work group. In males, it was 54 % in current weight less than 60 kg group, 19% in 60-70 kg group, 15% in 70-80 kg group and 23% in over 80 kg group. In females, it was 76% in current weight less than 50 kg group, 67% in 50-60 kg group, 63% in 60-70kg group, 30% in over 70 kg group. It was 56% in low body weight group, 41% in normal weight group and 58% in over weight group in their 25-year-old. It was 61% in normal body weight group, 43% in overweight group. It was 41% in non-fracture history group, 67% in once fracture group,74% in fracture history more than twice group. It was 60% in mother humpback history group, and 47% in no history of mother humpback group. Logistic regression analysis showed that gender, age,history of fracture, mother＇s humpbacked history, disease of internal secretion and metabolism system were the risk factors for OP. Conclusions The occurrence of OP is related with many factors in aged people at Beicai Town in Shanghai, especially for the aged women, who suffer from diseases of internal secretion and metabolism, and has the history of fracture and mother＇s humpbacked, the attention should be payed to the prevention and treatment of OP.