心理干预对不稳定心绞痛伴抑郁状态患者的疗效

Effect of Psychological Intercention to Unstable Angina Patients with Depression

目的:观察心理干预对不稳定心绞痛(UA)患者抑郁情绪及心肌缺血的影响。方法:选择我院心内科及老年病科收治的UA伴抑郁状态患者90例,将其随机分为干预组和对照组各45例;对照组予以常规心绞痛药物治疗,干预组在常规药物治疗基础上给予心理干预,抑郁状态严重者予以适量抗抑郁药物,疗程1个月;治疗前后应用Zung抑郁自评量表(SDS)及汉密尔顿抑郁量表(HRSD)进行评估,并应用24h动态心电图(Holter)测算心肌缺血总负荷(TIB)。结果:治疗后SDS评分:干预组(21.13±5.14),对照组(36.51±6.52),两组比较有显著性差异(P<0.05)。HRSD评分:干预组(9.32±3.64),对照组(17.44±5.93),两组比较有显著性差异(P<0.01)。TIB:干预组(14.85±10.86)mm/min,对照组(22.84±10.24)mm/min,两组比较有显著性差异(P<0.05)。结论:心理干预能明显消除UA患者的抑郁情绪,改善心肌供血。

Objective：To observe psychological intervention to unstable angian patients with depression and its effect to myocardial ischemia.Methods：90 cases of unstable angian patients with depression were randomly divided into intervention group and control group（each group of 45 cases）.Controls were treated by conventional angian drug therapy,and intervention group was given by psychological intervention in a basic treatment.The therapy lasted one month.Before and after treatment we used Zung depression self rating scale applications（SDS）,Hamiltom depression scale（HRSD）and application of dynamic electrocardiogram myocardial ischemia total load（TIB） to evaluate.Results：After the treament,SDS scores of intervention group and control group were（21.13±5.14）and（36.51±6.52）respectively.HRSD scores of the two group were（9.32±3.64）and（17.43±5.92）respectively.TIB of the two group were（14.85±10.86）mm/min and（22.84±10.24）mm/min respectively.There were all significant differences between the two group（P〈0.05）.Conclusion：Psychological intercention can eliminate the depression in UA patients and improve myocardial ischemia.