期刊文献+

绝经前女性与同年龄组男性冠心病病人临床特点与冠状动脉病变的对比分析 被引量:1

下载PDF
导出
摘要 目的探讨绝经前女性冠心病病人的临床和冠脉病变特点。方法选择21例在我院经冠状动脉造影确诊的绝经前女性冠心病病人为研究组,及同期在我院经冠状动脉造影确诊的32例年龄匹配的男性冠心病病人为对照组。分别对其临床特点及冠状动脉病变的特征进行比较。结果两组年龄相近,绝经前女性组高脂血症、糖尿病比例显著高于对照组(P<0.05),吸烟史显著低于对照组(P<0.05);两组高血压、家族史比例无统计学意义(P>0.05)。绝经前女性组临床表现以心绞痛为主,对照组以急性心肌梗死为主。两组均以单支病变为主,但病变支数无论是单支,还是双支及多支均无统计学意义(P>0.05)。结论绝经前女性冠心病病人危险因素相对较多,临床表现以心绞痛为主,急性心肌梗死很少。
出处 《中西医结合心脑血管病杂志》 2010年第10期1161-1162,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
  • 相关文献

参考文献10

  • 1Rosano GM,Vitale C,Silverstri A,et al.Metabolic and vascular effect of progestins in postmenopausal women:Implication for cardioprotection[J].Maturitas,2003,46(Suppl1):17.
  • 2Gurevitz O,Jonas M,Boyko R,et al.Clinical profile and long-term prognosis of women≤50 years of age referred for coronary angiography for evaluation of chest pain[J].Am J Cardiol,2000,85:806-809.
  • 3丁荣晶,贾三庆,王雷,李宏伟,南芳,张宇晨,陈辉,王永亮.绝经前女性冠心病患者危险因素及临床特点分析[J].医学临床研究,2006,23(11):1788-1790. 被引量:8
  • 4Mendelsohn ME,Karas RH.The protective effects of estrogen on the cardiovascular system[J].N Engl J Med,1999,340:1801-1811.
  • 5Asahara T,Murohara T,Sullivan A,et al.Isolation of putative endothelial cells for angiogenesis[J].Science,1997,275:964.
  • 6朱定君,石蓓,许官学,刘西平,易晓君,郭艳.绝经前后妇女外周血内皮祖细胞数量和功能的对比研究[J].现代妇产科进展,2008,17(1):55-58. 被引量:4
  • 7黄楷森,何顶秀,黄德嘉.雌激素与冠心病——通过内皮祖细胞发挥有益作用[J].心血管病学进展,2008,29(6):858-862. 被引量:7
  • 8Hill JM,Zalos G,Halcox JP,et al.Circulating endothelial progenitor cells,vascular function,and cardiovascular risk[J].N Engl J Med,2003,348:593-600.
  • 9Fadini GP,Kreutzenberg SD,Albiero M,et al.Gender differences in endothelial progenitor cells and cardiovascular risk profile[J].Arteriosclerosis Thrombosis and Vascular Biology,2008,28:997-1004.
  • 10Lawesson SS,Stenestrand U,Lagerqvist B,et al.Gender perspective on risk factors,coronary lesions and long-term outcome in young patients with ST-elevation myocardial infarction[J].Heart,2010,96:453-459.

二级参考文献44

  • 1Kalka C,Masuda H,Takahashi T,et al. Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects[J]. Circ Res ,2000,86(12) : 1198-1202.
  • 2Shalaby F, Rossant J,Yamaguehi TP, et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice[ J ]. Nature, 1995,376 ( 6535 ) :62- 66.
  • 3Fong GH, Rossant J,Cerlsenstein M,et al. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vasoular endothelium[J ]. Nature, 1995, 376(6535) :66-70
  • 4Ferrara N,Carver-Moore K, Chen H,et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene [ J ]. Nature, 1996, 380 (6573) :439-442.
  • 5Ioakim S, Sullivan AB. Estrogen-receptor-me,tiated inhibition of human endothelial ceil apoptosis [ J ]. Circulation, 1997,95 : 1505 - 1514.
  • 6Imanishi T, Hano T,Nishio I. Estrogen reduces angiotensin Ⅱ-induced acceleration of senescence in endothelial progenitor cells[ J]. Hypertens Res Clin Exp,2005,28(3) :263-271.
  • 7hnanishi T,Kobayashi K,Hano T,et al. Effect of estrogen on differentiation and senescence in endothelial progenitor cells derived from bone marrow in spontaneously hypertensive rats[ J]. Hypertens Res Clin Exp,2005,28(9) :763-772.
  • 8Silvestre JS, Gojova A, Brun V, et al. Transplantation of bone marrow-derived mononuclear cells in isehemic apolipoprotein E-knockout mice accelerates atherosclerosis without altering plaque composition [ J]. Circulation, 2003, 108 : 2839-2842.
  • 9George J, Atek A, Abashidze A, et al. Transfer of endothelial progenitor and bone marrow cells influences atherosclerotic plaque size and composition in apolipoprotein E knockout mice[J]. Arterioscler Thromb Vase Biol,2005,25 (12) :2636-2641.
  • 10Yoon YS, Park JS, Tkebuchava T, et al. Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction [ J ]. Circulation,2004,109 (25) :3154-3157.

共引文献15

同被引文献7

  • 1卫生部心血管病防治研究中心.中国心血管病报告2012[M].北京:中国大百科全书出版社,2013:8.
  • 2Mosca L, Manson JE, Sutherland SE,et al. Cardiovas-cular disease in women:a statement for healthcare profes-sionals from the American Heart Association. WritingGroup[J]. Circulation,1997,96(07) :2468-2482.
  • 3中华人民共和国卫生部.中国卫生统计年签2011[M].北京:中国协和医科大学出版社,2011.
  • 4中华人民共和国卫生部.中国卫生统计年签2012[M].北京:中国协和医大学出版社,2012.
  • 5Kannel W B. Metabolic risk factrs for coronary heartdisease in women : Prespective from the Framingham stuty[J]. Am Heart J, 1987,114(02) :413-419.
  • 6Wiseth R,Dale A C,Nilsen T I,et al. Diabetes melli-tus and risk of fatal ischaemic heart disease by gender : 18years follow [J]. European Heart Journal,2007,28 (23 ):2924-2929.
  • 7Culleton B F, Larson M G,Kannel W B, et al. Serumuric acid and risk for cardiovascular disease and death: TheFramingham Heart Study[J]. Annals of Internal Medicine,1999,131(01):7-13.

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部