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血浆叶酸、维生素B_(12)水平与脑梗死的关系 被引量:1

Relationship between plasma folate and vitamin B12 levels with cerebral infarction
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摘要 目的探讨血浆叶酸(Fa)、维生素B12(VitB12)水平与脑梗死的关系。方法采用电化学发光免疫分析法检测70例脑梗死患者(脑梗死组)和40例健康体检人员(对照组)的Fa、VitB12浓度,并将两组结果进行比较。结果脑梗死组Fa、VitB12浓度均低于对照组,差异有统计学意义(P<0.01)。结论血浆Fa、VitB12缺乏可能是脑梗死的又一独立危险因素。 Objective To investigate the plasma folic acid(Fa),vitamin 12 levels with cerebral infarction.Methods Electrochemiluminescence immunoassay was used to detect plasma folate,vitamin B12 levels in 70 patients with cerebral infarction and 40 normal controls.The results were compared between the two groups.Results In the patients with cerebral infarction,plasma folic acid and vitamin B12 levels were lower than those in the control group with significant difference(P〈0.01).Conclusion Both plasma folate and vitamin B12 may be the independent risk factors for cerebral infarction.
出处 《检验医学与临床》 CAS 2010年第20期2223-2223,2225,共2页 Laboratory Medicine and Clinic
关键词 叶酸 维生素B12 脑梗死 电化学发光法 folic acid vitamin B12 cerebral infarction electrochemical luminescence
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  • 1Pierdomenico SD, Bucci A, Lapenna D, et al. Circulating homocysteine levels in sustained and white coat hypertension. J Hum Hypertens. 2003, 17(3):165.
  • 2Darius H, Pittrow D, Haber1 R et al. Are elevated homocysteine plasma levels related to peripheral arterial disease? Results from a cross-sectional study of 6880 primary care patients. Eur J Clin Invest. 2003, 33(9):751.
  • 3Aronow WS. Homocysteine. The association with atherosclerotic vascular disease in elder persons. Geriatrics. 2003, 58(9):22.
  • 4Ambrosi P, Barlatier A, Artaud-Navarro A, et al. Homocysteine and coronary events in coronary disease patients. Ann Cardiol Angeiol. 1999, 48(3):185.
  • 5Stemler TS, Osbome JA, Taraki O, et al. Advers vascular effects of homocysteine are modulated endothelium derived relaxing factor and related oxides of nitogen. J Clin Invest. 1995, 75:132.
  • 6Naurath HJ, Joosten E, Riezler R, et al. Effects of vitamin B12, folate and vitamin B6 supplements in elderly people with normal serum vitamin concentrations. Lancet. 1995, 346(8967):85.
  • 7Refsum H,Ueland PI,Nygard O,et al.Homocysteine and Cardiovascular disease.Annu Rev Med,1998,49:31~62.
  • 8Wuillemin WA,Solenthaler I.Hyperhomocysteinemia a risk factor for arterial and venous thrombosis.Vasa,1999,28(4):306.
  • 9Genest J Jr Hyperhomocysteinemia-determining factors and treatment.Can J Cardiol,1999,15(supple 13):35B~38B.
  • 10Fodinger I,Horl WH.Sunder Plassmann G,Melecular biology of 5,10-Methylenetetrahydrofolate reductase.J Nephrol,2000,13(1):20~33.

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