摘要
采用价格仅是乙酰氯１／３的乙酸酐为酰化剂，并选用吡啶为溶剂兼缩合剂，替代二氧六环及氢氧化钙，合成１，３－二苯基－４－乙酰基－５－吡唑酮，在不减少得率的前提下，使制备成本大幅度降低。
Acetic anhydride, whose price is only 1/3 of that of acetyl chloride, is used as the acylation agent. And instead of dioxane and calcium hydroxide, pyridine is chosen to be the condensation agent as well as the solvent. Thus, without reducing the yield, the cost of the preparation for 1,3diphenyl4acetyl5pyrazolone is greatly reduced and the routine is even easier.
出处
《北京轻工业学院学报》
1999年第1期19-23,共5页
Journal of Beijing Institute of Light Industry
关键词
DPAP
螯合萃取剂
二苯基
乙酰基
吡唑酮
萃取剂
acetic anhydride
pyridine
1,3diphenyl5pyrazolone
1,3diphenyl4acetyl5pyrazolone
acylation
