1Mercher T,Cornejo MG,Sears C,et al.Notch signaling specifies megakaryocyte development from hematopoietic stem cells[J].Cell Stem Cell,2008,3(3):314-326.
2Rampal R,Luther KB,Haltiwanger RS.Notch signaling in normal and disease states:possible therapies related to glycosylation[J].Curt Mol Med,2007,7(4):427-445.
3Dsouza B,Miyamoto A,Weinmaster G.The many facets of Notch ligands[J].Oncogene,2008,27(38):5148-5167.
4Bouras T,Pal B,Vaillant F,et al.Notch signaling regulates mammary stern cell function and luminal cell fate commitment[J].Cell Stem Cell,2008,3(4):429-441.
5Sainson RC,Harris AL.Regulation of angiogenesis by homotypic and heterotypic Notch signalling in endothelial cells and pericytes:from basic research to potential therapies[J].Angiogenesis,2008,11(1):41-51.
6Sainson RC,Harris AL.Anti-DII4 therapy:can we block tumour growth by increasing angiogenesis?[J].Trends Mol Med,2007,13(9):389-395.
7Demarest RM,Ratti F,Capobianco AJ.It′s T-ALL about Notch[J].Oncogene,2008,27(38):5082-5091.
8Jundt F,Schwarzer R,Dorkcn B.Notch signaling in leukemias and lymphomas[J].Curt Mol Med,2008,8(1):51-59.
9Vilimas T,Mascarenhas J,Palomero T,et al.Targeting the NF-κ B signaling pathway in Notch1-induced T-cell leukemia[J].Nat Med,2007,13(1):70-77.
10Kageyama R,Ohtsuka T,Shimojo H,et al.Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition[J].Nat Neurosci,2008,11(11):1247-1251.
2Skomedal H,Kristensen G B,Lie A K,et al.Aberrant expression of the cell cycle associated proteins TP53,MDM2,p21,p27,cdk4,cyclin D1,RB,and EGFR in cervical carcinomas[J].Gynecol Oncol,1999,73:223-228.
3Ellisen L W,Bird J,West DC,et al.TAN-1,the human homolog of the Drosophila notch gone,is broken by chromosomal translocations in T lymphoblastic neoplasms[J].Cell.1991,66(4):649-661.
4Axelson H.Notch signaling and cancer:emerging complexity[J].Semin Cancer Biol.2004,14(5):317-319.
5Morimura T.Goitsuka R,Zhang Y,et al.Cell cycle arrest and apoptosis induced by Notchl in B cells[J].J Biol Chem,2000,275:36 523-36 531.
6Politi K,Feirt N,Kitajewski J.Notch in mammary gland development and breast cancer[J].Semin Cancer Biol,2004,14:341-347.
7Zagouras P,Stifani S,Blaumueller C M,et al.Alterations in Notch signaling in neoplastic lesions of the human cervix[J].Proc Natl Acad Sci USA,1995,92(14):6414-6418.
8Rangarajan A,Syal R,Selvarajah S,et al.Activated Notchl signaling cooperates with papillomavims oncogenes in transformation and generates resistance toapoptosis on matrix withdrawal through PKB/Akt[J].Virology,2001,286(1):23-30.
9Tonon G,Modi S,Wu L,et al.t(11,19)(q21;p13)translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway[J].Nat Genet,2003,33(2):208-213.
10Nicolas M,Wolfer A,Raj K,et al.Notchl functions as a tumor suppressor in mouse skin[J].Nat Genet,2003,33(3):416-421.
