摘要
目的通过对重症多神经病变(C IP)患者最大吸气压(M IP)和气道闭合压(P0.1)的监测,探讨呼吸力学指标变化规律及意义。方法以综合ICU收治的机械通气时间≥7d的患者为研究对象,测定患者入住ICU第1、3、5、7d的M IP和P0.1。研究组患者入住ICU第7d行肌电图检查1次,按肌电图检查结果将患者分为C IP组和非C IP组,比较C IP组和非C IP组之间M IP及P0.1的差异。结果 CIP组第7d的P0.1高于非C IP组,两组差异有统计学意义;C IP组第5、7d的M IP低于非C IP组,两组差异有统计学意义;受累神经部位≥3的C IP患者第7d的P0.1水平高于受累神经部位≤2的C IP患者,受累神经部位≥3的C IP患者第7d的M IP水平低于受累神经部位≤2的C IP患者,两组差异均有统计学意义。结论并发C IP的危重病患者呼吸肌力受到影响,动态监测M IP和P0.1可以作为评估C IP病情严重程度的指标。
Objective To study the maximum inspiratory pressures（MIP） and 0.1 second airway occlusion pressure（P0.1） change in critical illness polyneuropathy（CIP） patients.Methods ICU patients who required mechanical ventilation for more than 7 days were enrolled in this study.MIP and P0.1 were measured in the 1st,the 3rd,the 5th and the 7th day.The electromyogram examination was performed in the 7th day.According to the results of electromyogram,patients were classified as CIP group and no-CIP group.MIP and P0.1 were compared between CIP group and no-CIP group.Results P0.1 in CIP group was higher than that in no-CIP group at the 7th day.MIP in CIP group was lower than that in no-CIP group at the 5th and the 7th day.P0.1 was higher in CIP patients with over 3 parts of nerves injured than that below 2 parts of nerves injured in the 7th day.MIP was lower in CIP patients with over 3 parts of nerves injured than that below 2 parts of nerves injured in the 7th day.The above differences all had the statistically significant.Conclusion Dynamic monitoring of MIP and P0.1 in patients with CIP would be parameters that may show the severity of the disease.
出处
《宁夏医学杂志》
CAS
2010年第10期892-893,共2页
Ningxia Medical Journal
关键词
重症多神经病变
危重病
最大吸气压
气道闭合压
Critical illness polyneuropathy （CIP）
Critically illness
Maximum inspiratory pressures （MIP）
O. 1 second airway occlusion pressure （ Po , ）
