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Ets-1在不同食管病变组织中的表达及意义 被引量:2

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摘要 目的探讨Ets-1在食管不同病变组织中的表达及意义。方法应用逆转录-聚合酶链反应(RT-PCR)和Westernblotting方法检测62例食管鳞癌、20例癌旁不典型增生组织及40例食管正常黏膜组织中Ets-1 mRNA和蛋白的表达情况。结果 Ets-1 mRNA和蛋白在正常食管黏膜、癌旁不典型增生及食管鳞癌组织中的相对含量均依次升高,组间比较差异有统计学意义(0.728±0.097、0.751±0.084、0.779±0.046,P<0.05;0.023±0.011、0.208±0.010、0.733±0.015,P<0.05)。结论 Ets-1在食管鳞癌组织中表达显著升高。
出处 《重庆医学》 CAS CSCD 北大核心 2010年第20期2777-2779,共3页 Chongqing medicine
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参考文献11

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