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瑞舒伐他汀治疗高龄老年人高脂血症的疗效及安全性观察 被引量:11

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摘要 目的观察瑞舒伐他汀治疗高龄老年人(≥80岁)高脂血症的疗效及安全性。方法选择45例高龄老年高脂血症患者口服瑞舒伐他汀10mg/d,疗程12周。观察治疗前后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、谷丙转氨酶(ALT)、尿素氮(BUN)、肌酐(Cr)、肌酸激酶(CK)、血常规、心电图等变化以及不良反应。结果瑞舒伐他汀降低TC、TG、LDL-C,升高HDL-C的作用显著(治疗后分别为4.02±0.46、1.08±0.76、1.96±0.67、1.48±0.31mmol/L),与治疗前(分别为5.80±0.56、2.39±0.38、3.26±0.85、1.20±0.21mmol/L)比较,差异有统计学意义(P均<0.05)。5例患者出现轻微不良反应,但均能够耐受。结论瑞舒伐他汀治疗老年高脂血症疗效可靠,且不良反应小,适合老年高脂血症患者使用。
出处 《中华保健医学杂志》 2010年第5期392-393,共2页 Chinese Journal of Health Care and Medicine
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