摘要
目的:评价替米沙坦对IgA肾病患者蛋白尿的影响。方法:选择30例IgA肾病患者为研究对象,将其随机分为治疗组和对照组各15例,治疗组应用替米沙坦治疗,对照组应用常规治疗。观察时间为6个月。观察24h尿蛋白定量、血压变化、血肌酐、尿素氮的变化。结果:治疗6个月后,治疗组与对照组24h尿蛋白均减少,治疗组较对照组疗效更显著。结论:替米沙坦能够减少IgA肾病患者尿蛋白量,对阻止和延缓疾病的进展、减少终末期肾病的发生率具有较好的作用。
Objective:To evaluate the efficacy of telmisartan on IgA nephropathy proteinuria.Methods:30 cases of patients with IgA nephropathy were randomly divided into two groups,the treatment group 15 cases were given telmisartan treatment,the control group 15 cases were given conventional treatment.Observed 6 months.Observed the 24-hour urine protein quantification,blood,serum creatinine,urea nitrogen.Results:After 6 months treatment,the 24-hour urine protein of the treatment group and the control group both decreased,the effect of the treatment group was better than that of the control group.Conclusion:Telmisartan can reduce urine protein of IgA nephropathy,it has good effects to block and slow down the progress of the disease,reduce end-stage renal disease incidence.
出处
《中国当代医药》
2010年第30期43-44,共2页
China Modern Medicine