甲钴胺联合七叶皂苷钠治疗急性特发性面神经麻痹临床分析

Clinical analysis on methycobal union sodium aescinate in treatment of acute idiopathic facial palsy

目的:探讨甲钴胺联合七叶皂苷钠治疗急性特发性面神经麻痹的有效性与安全性。方法:选择2007年6月～2009年12月首次发病诊断的急性特发性面神经麻痹患者98例,并随机分为观察组49例(甲钴胺联合七叶皂苷钠加基础治疗),对照组49例(泼尼松联合基础治疗),基础治疗包括多种维生素、抗病毒治疗、针灸、理疗等。结果:观察组痊愈率为53.06%,总有效率为95.92%;对照组痊愈率为24.49%,总有效率为81.63%;两组比较,差异有统计学意义(P<0.05)。结论:甲钴胺联合七叶皂苷钠治疗急性特发性面神经麻痹能使受损的面神经早日康复,有效改善其预后,且无不良反应。

Objective：To discuss the availability and the safty on the methycobal union sodium aescinate in the treatment of acute idiopathic facial palsy.Methods：98 cases with acute idiopathic facial palsy in the first diagnosis were chosen from June 2007 to December 2009,and randomly divided into the observation group for 49 cases （methycobal union sodi um aescinate with the basic treatment）,49 cases in the control group （metacortandracin jointed the foundation treatment）,the foundation treatment included vitamins and antiviral therapy,acupuncture,medical treatment,etc.Results：The cure rate in the observation group was 53.06%,total effective rate was 95.92%.The cure rate in the control group was 24.49%,total effective rate was 81.63%,the two groups had statistics difference （P0.05）.Conclusion：Methycobal union sodium aescinate treatment for acute idiopathic facial palsy can make the facial nerve be fine,and can improve its prognosis,and also have no untoward effect.