Laboratory Diagnostic Strategy for Thrombophilia

Thrombophilia is described as a tendency to develop thrombosis as a consequence of predisposing factors that may be genetically determined, acquired, or both. The risk factors associated with venous thromboembolism are different from those associated with arterial thrombosis.

Thrombophilia is described as a tendency to develop thrombosis as a consequence of predisposing factors that may be genetically determined, acquired, or both. The risk factors associated with venous thromboembolism are different from those associated with arterial thrombosis. Venous and arterial thromboses are also distinct clinical entities that differ in the microenvironment of clot formation and the structure of the clots formed. Therefore, the tests to be used in laboratory investigation of these two conditions are different.