PCOS患者血清ADP和INS水平的相关性分析

Study on the Relationship Between the Serum Adiponectin and Insulin Levels in Patients with Polycystic Ovary Syndrome (PCOS)

目的:探讨了多囊卵巢综合征(PCOS)患者血清脂联素(ADP)和胰岛素(INS)水平的相关性。方法:采用放射免疫分析对36例PCOS患者进行了血清ADP和INS测定,并与35名正常人为对照。结果:PCOS患者血清ADP水平非常显著地低于正常人组(P<0.01),而血清INS水平则显著地高于正常人组(P<0.01)。两者呈明显的负相关(r=-0.5034,P<0.01)。结论:PCOS患者血清ADP和INS水平密切相关,对判断病情的严重程度、病情的发展均具有重要的临床价值。

Objective To study the relationship between the serum adiponectin and insulin levels in patients with polycystic ovary syndrome （PCOS） .Methods Levels of serum adiponectin and insulin were detected with RIA in 36 patients with polycystic ovary syndrome and 35 controls.Results In the patients,the serum adiponectin levels were significantly lower than those in controls （P〈 0.01） ,while the serum insulin levels were significantly higher （P〈 0.01） .Serum adiponectin and insulin levels were mutually negatively correlated （r =-0.5034,P〈 0.01） .Conclusion There is a close relationship between the serum adiponectin and insulin levels in patients with polycystic ovary syndrome.