原发性高血压微量白蛋白尿与颈动脉粥样硬化关系分析

目的探讨原发性高血压(essential hypertension,EH)微量白蛋白尿(microalbuminuria,MAU)与颈动脉粥样硬化(carotid atherosclerosis,CAS)的关系。方法 215例高血压患者分别测定24小时尿微量白蛋白含量,并行颈动脉超声等检查。按尿微量白蛋白水平分为两组,正常组116例,微量白蛋白尿组99例。结果微量白蛋白尿组颈动脉内膜增厚及斑块形成率均高于正常组(P<0.05)。结论原发性高血压患者尿微量白蛋白水平与颈动脉粥样硬化及硬化程度密切相关。尿微量白蛋白水平越高,颈动脉粥样病变越严重。

Objective To observe the relation between essential hypertension microalbuminuria and carotid atherosclerosis. Methods 215 patients of EH were divided into two groups according to the MAU level. 116 patients were normoalbuminuria group,99 patients were MAU group. MAU were measured by immune nephelometry and turbidimetry; IMT were measured by color Doppler ult rasound.Results The level of microalbuminuria of group of carotid atherosclerosisis higher significantly than normal group （P0.05）. Conclusion The level of microalbuminuria is positive correlation with degree of carotid atherosclerosis,more higher the level of micr oalbuminuria,more,more serious carotid atherosclerosis.