宽叶大戟化学成分研究

Chemical constituents of Euphorbia latifolia

目的:研究宽叶大戟的化学成分。方法:对宽叶大戟全草95%乙醇提取物的乙酸乙酯萃取部分进行色谱分离,根据光谱数据和理化性质确定各化合物的结构。结果:分离并鉴定了9个化合物,分别为:宽叶大戟素(1),山柰素(2),木犀草素(3),槲皮素(4),胡萝卜苷(5),山柰素-3-O-β-D-葡萄糖苷(6),槲皮素-3-O-β-D-葡萄糖苷(7),3,4-二羟基苯甲酸(8)和没食子酸(9)。结论:化合物1为新化合物,化合物3和8为首次从本植物中分离得到。

AIM：To investigate the chemical constituents of Euphorbia latifolia.METHODS：The constituents of EtOAc-soluble portion of 95% ethanol extract were isolated and purified by means of chromatography.Compounds were identified by their physical characteristics and spectral features.RESULTS：Nine compounds were isolated and identified as latifolin（1）,kaempferol（2）,luteolin（3）,quercetin（4）,daucosterol（5）,kaempferol-3-O-β-D-glucoside（6）,quercetin-3-O-β-D-glucoside（7）,3,4-dihydroxybenzoic acid（8） and gallic acid（9）.CONCLUSION：Compound 1 is a new compound.Compounds 3 and 8 are isolated from this plant for the first time.