生脉胶囊治疗慢性充血性心力衰竭临床疗效的AHP综合评价

Synthetic evaluation of the clinical effect of the Shengmai capsule for treatment of chronic congestive heart failure using analytic hierarchy process

目的探讨中药(新药)临床试验研究的临床疗效综合评价方法和技术路线。方法应用AHP(analytic hierarchy process)多属性综合评价的方法,对生脉胶囊治疗慢性充血性心力衰竭的临床疗效进行多指标(多属性)临床疗效综合评价。结果生脉胶囊对慢性充血性心力衰竭的临床治疗作用是正向性的。结论建立了合理的方法和模型来综合评价中药(新药)的临床疗效并为其疗效等级排序。

Objective To explore the approaches and techniques for synthetic evaluation of the clinical therapeutic effect of new Chinese herbal medicine in clinical trials.Methods In a double-blind,randomized,and placebo-controlled clinical trail,analytic hierarchy process（AHP） was applied to evaluate the clinical therapeutic effect of Shengmai capsule in the treatment of chronic congestive heart failure.Results Shengmai capsule produced positive therapeutic effect on chronic congestive heart failure.Conclusion A feasible method is established for evaluating and grading the clinical therapeutic effect of Chinese herbal medicine.