泪腺上皮性肿瘤113例临床病理学分析

Clinical and pathological analysis of 113 cases of lacrimal epithelial tumors

目的 探讨泪腺上皮性肿瘤组织病理学类型和临床特征.方法 回顾性病例研究重新复习天津眼科医院病理科自1980年至2009年间收检的113例泪腺上皮性肿瘤的临床和病理学资料,参照WHO关于唾液腺肿瘤的分类和诊断标准,分析泪腺上皮性肿瘤的类型和临床病理学特点.结果 113例泪腺上皮性肿瘤中,多形性腺瘤73例（64.6%）,腺样囊性癌23例（20.4%）,癌在多形性腺瘤中9例（8.0%）,其他类型的上皮性肿瘤均为恶性,共8例（7.0%）.结论 泪腺上皮性肿瘤有不同的病理类型,其临床特点、治疗和预后有很大区别,正确和详细的病理诊断可对临床治疗起到指导意义.

Objective To investigate the histopathological and clinical features of lacrimal epithelial tumors. Methods A retrospective study of 113 cases of lacrimal epithelial tumors from Ophthalmic Pathology Laboratory, Tianjin Eye Hospital （1980 to 2009） was performed to investigate the clinical features, histopathological classification and prognosis, which based on the current World Health Organization classification of salivary gland tumors. Results In the cases, pleomorphic adenoma was the most common tumor （73 cases,64.6%）, followed by adenoid cystic carcinoma （23 cases, 20.4%）, carcinoma ex pleomorphic adenoma（9 cases,8.0%） and other malignant epithelial tumors （8 cases, 7.0%）. Conclusions Epithelial tumors of lacrimal gland have different pathological types, each type has different clinical features, treatment and prognosis. The correct and detail pathological diagnosis is important for selecting the proper treatment and postoperative management.