纯音听阈甘油试验影响因素分析

Analysis of factors affecting the pure tone threshold glycerol test

目的:探讨纯音听阈甘油试验结果的影响因素及其阳性频率分布特征。方法:测试梅尼埃病患者口服甘油前后纯音听阈的改变,分析其阳性率、阳性频率分布以及最大幅度的阈值改变的出现时间。结果:纯音听阈甘油试验阳性率为72.09%,其中听阈下降阳性率为47.67%,听阈回跳阳性率为24.42%;听阈下降的幅度为(17.41±9.92)dB,回跳幅度为(13.53±4.64)dB,两者差异有统计学意义。各频率按照阳性率由高到低依次分布为250Hz、125Hz、500Hz、1kHz、4kHz、2kHz、8kHz;阳性的最大听阈改变主要出现在口服甘油后2～3h。结论:纯音听阈甘油试验阳性率受受试对象及时机的选择、判断标准等因素影响;甘油试验阳性主要分布在低频区。

Objective：To probe the factors that affect the pure-tone threshold glycerol test and the distribution of frequencies in positive glycerol test.Method：We tested the pure-tone threshold before and after glycerol intake in patients with Meniere＇s disease,and then analyzed the positive rates、distribution of positive frequencies and the time when the maximum threshold changes appeared.Result：The positive rate of pure-tone glycerol test was 72.09%,of which the threshold descending rate was 47.67%,and the threshold rebounding rate was 24.42%; the pure-tone threshold changes of descending group and rebounding group were（17.41±9.92）dB,（13.53±4.64）dB respectively,and the differences were significant.The distribution of positive frequencies were 250Hz, 125Hz,500Hz,1kHz,4kHz,2kHz,8kHz in descending order.The maximum pure-tone threshold changes mostly appeared within 2 or 3 hours after glycerol intake.Conclusions：Patient selection,test occasion and the judgement criteria may affect the positive rate of glycerol test;the positive frequencies distribute in the low-frequency region mainly;the maximum pure-tone threshold changes mostly appeare within 2 or 3hours after glycerol intake.