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噬血细胞综合征患者血清LDH和β_2-MG检测的临床意义 被引量：2

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摘要 目的探讨噬血细胞综合征(HPS)患者血清乳酸脱氢酶(LDH)和血清β2-微球蛋白(β2-MG)测定的临床意义。方法分别采用速率法和放免法测定31例HPS患者和17名正常对照者血清LDH和β2-MG水平。结果正常对照组与HPS组、HPS治疗缓解组与初发组、非肿瘤相关性HPS(NT-HPS)与肿瘤相关性HPS(T-HPS)组的β2-MG水平相比,后者均明显高于前者(P<0.05);而LDH在前2组中差异有统计学意义(P<0.05),但在NT-HPS和T-HPS之间差异无统计学意义(P>0.05)。结论β2-MG和LDH的检测有助于HPS诊断和疗效的评价。而且β2-MG还可以作为鉴别NT-HPS和T-HPS的一个辅助指标。
作者 方涵 谢军军 王剑超 童向民
机构地区 台州市第一人民医院检验科 杭州市师范大学 浙江省新华医院 浙江大学医学院附属第一医院血液科
出处 《检验医学》 CAS 北大核心 2010年第10期807-809,共3页 Laboratory Medicine
基金 浙江省科技厅资助项目(2007C33083) 浙江省自然基金资助项目(Y2080353) 杭州市科技局资助项目(20090833B24 20070114 2008CA031)
关键词 乳酸脱氢酶 Β2-微球蛋白 噬血细胞综合征
分类号 Q554 [生物学—生物化学]
  • 相关文献

参考文献10

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共引文献44

同被引文献32

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引证文献2

二级引证文献6

检验医学
2010年 第10期

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