1,25二羟基维生素D3生物学功能研究进展

Progress in research on biological function of 1,25 dihydroxy vitamin D3

维生素D3抗婴儿佝偻病的疗效已尽人皆知,而1,25二羟基维生素D3是维生素D3的活性形式,通过近年研究,它不仅具有调节钙磷代谢的作用,还具有调控细胞有丝分裂,抑制肿瘤细胞生长,发挥免疫调节,调控肾素-血管紧张素系统（RAS）从而调节血压,改善糖代谢等多种生物学功能.现就近年来有关其生物学功能方面的研究进展作以综述.

1,25dihydroxy vitamin D3 is the biologically active form of vitamin D3. It not only regulates metabolisms of cacium and phosphorus, but also has other important biological functions, such as restraining growth of tumor cells, excerting immunoregulation, suppressing rennin-angiotesin-system so regulating blood pressure, improving glucose metabolism, etc. This article reviewed progress in recent research on its biological functions.