保留灌肠治疗溃疡性结肠炎110例临床观察

Clinical observation of 110 cases of ulcerative colitis treated by preserving clyster

目的观察110例保留灌肠治疗溃疡性结肠炎临床疗效。方法将110例患者随机分为两组。对照组55例口服柳氮磺胺吡啶(SASP)治疗。治疗组55例,口服SASP和甲硝唑+思密达+地塞米松保留灌肠治疗。两组均以1个月为1疗程,共治疗2个疗程。结果总有效率,治疗组94.5%,对照组78.2%。两组比较,差异有显著意义(P<0.05)。治疗后临床症状缓解情况及结肠镜检查结果治疗组与对照组的比较,差异均有显著性意义(P<0.05)。结论甲硝唑、地塞米松加思密达保留灌肠治疗UC疗效显著。

【Objective】To observe the clinical curative effect of 110 cases ulcerative colitis treated by preserving clyster.【Methods】We divided the 110 patients into two groups.One group of 55 patients took medicine of SASP.Another 55 patients used SASP,Metronidazole,Dexamethasone and Montmorillonite preserving clyster treatment for 2 months＇ period.【Results】The general efficiency effect rate of treatment group was 94.5%,the comparison group was 78.2%.The difference between the two groups had remarkable meanings（P0.05）.To compare the catabatic instance of clinical symptom and the colon lens check-up result of the two groups after the treatment,the difference of these two groups had remarkable meanings（P0.05）.【Conclusion】It has a remarkable curative effect to treat UC using Metronidazole,Dexamethasone and Montmorillonite preserving clyster.