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Wnt信号途径与类风湿关节炎 被引量:1

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摘要 类风湿关节炎(rheumatoid arthritis,RA)是一种累及周围关节为主的多系统性、炎症性的自身免疫性疾病,是国内最常见的风湿病之一,其发病机制尚未完全明确。wnt信号途径由一系列相互作用的分子组成,调控胚胎期四肢和关节的发育过程,近年研究发现此途径在RA发病机制中也发挥着重要作用。更多地了解wnt信号途径在RA中的作用,
出处 《中华风湿病学杂志》 CAS CSCD 北大核心 2010年第10期705-707,共3页 Chinese Journal of Rheumatology
基金 基金项目:国家自然科学基金(30901340)
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参考文献25

  • 1Staal FJ,Clevers HC.WNT signaling and haematopoiesis:a WNT-WNT situation.Nat Rev Immunol,2005,5:21-30.
  • 2Reya T,Clevers H.Wnt signalling in stem cells and cancer.Nature,2005,434:843-850.
  • 3Macdonald BT,Semenov MV,He X.Snapshot:Wnt/β-catenin signalling.Cell,2007,131:1204.
  • 4Staal FJ,Luis TC,Tiemessen MM,et al.WNT signaling in the immune system:WNT is spreading its wings.Nat Rev Immunol,2008,8:581-593.
  • 5Daniels DL,Weis WI.ICAT inhibits β-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300using independent structural modules.Mol Cell,2002,10:573-584.
  • 6Kikuchi A,Yamamoto H,Kishida S.Multiplicity of the interactions of Wnt proteins and their receptors.Cell Signal,2007,19:659-671.
  • 7Sen M,Lauterbach K,EI-Gabalawy H,et al.Expression and function of wingless and frizzled homologs in rheumatoid arthritis.PNAS,2000,97:2791-2796.
  • 8Sen M,Reifert J,Corr M,et al.Blockade of Wnt-5A/frizzled 5signaling inhibits rheumatoid synoviocyte activation.Arthritis Rheum,2001,44:772-781.
  • 9Diarra D,Stolina M,Polzer K,et al.Dickkopf-I is a master regulator of joint remodeling.Nat Med,2007,13:156-163.
  • 10Schett G,Zwerina J,David JP.The role of Wnt proteins in arthritis.Nat Clin Pract Rheumatol,2008,4:473-480.

二级参考文献10

  • 1Steinman RM.The dendritic cell system and its role in immunogenicity[].Annual Review of Immunology.1991
  • 2Imal Y,Yamakawa M.Morphology, function and pathology of follicular dendritic cells[].Pathology International.1996
  • 3Lambrecht BN,de Veerman M,Coyle AJ,et al.Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation[].The Journal of Clinical Investigation.2000
  • 4Hart DNJ.Dendritic cells: unique leukocyte populations which control the primary immune response[].Blood.1997
  • 5Thomas R,Quinn C.Functional differentiation of dendritic cells in rheumatoid arthritis: role of CD86 in the synovium[].J Immunol.1996
  • 6Summers KL,O′Donnell JL,Heiser A,et al.Synovial fluid transforming growth factor beta inhibits dendritic cell-T lymphocyte interactions in patients with chronic arthritis[].Arthritis and Rheumatism.1999
  • 7Banchereau J,Steinman RM.Dendritic cells and the control of immunity[].Nature.1998
  • 8Thomas R,Lipsky PE.Dendritic cells : origin and differentiation[].Stem Cells.1996
  • 9Lindhout E,Van Eijk M,Van Pel M,et al.Fibroblast-like synoviocytes from rheumatoid arthritis patients have intrinsic properties of follicular dendritic cells[].J Immunol.1999
  • 10Williams L,Efner W,Hart DNJ.Isolation and function of human dendritic cells[].International Review of Cytology.1994

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  • 1Szlarna G, Kond6s K, Trexler M, et al. WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity [ J ]. FEBS J,2010,277(24) : 5040-5050.
  • 2韩沙沙,王晓芝.血管生成素4的研究进展[J].医学综述,2011,17(6):807-809. 被引量:1

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