4Mac ArthurRD, Miller M, AlbertsonT, etal. Adequacy of early empiric antibiotic treatment and survival in severe sepsis: experiencc from the MONARCS trial[J]. Clin Infect Dis,2004,38(2) : 284 -288.
5Monnerel G, Lepape A, Voirin N, et al. Persisting low monocyte human leukoeyle antigen DR expression predicts mortality in septic shock[J].Intensive Care Med,2006,32(9) :1175.
3Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med, 2003, 348(2):138-150.
4Efron PA, Tinsley K, Minnich DJ,et al. Increased lymphoid tissue apoptosis in baboons with bacteremic shock. Shock, 2004, 21(6):566-571.
5Dellinger RP, Carlet JM, Masur H,et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock. Crit Care Med, 2004, 32(7):858-873.
6Bernard GR, Vincent JL, Laterre PF,et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med, 2001, 344(10):699-709.
7Tracey KJ. The inflammatory reflex. Nature, 2002, 420(6917): 853-859.
8Wilkinson JD, Pollack MM, Glass NL, et al. Mortality associated with multiple organ system failure and sepsis in pediatric intensive care unit. J Pediatr ,1987, 111:324-328.
9Leteurtre S, Martinot A, Duhamel A, et al. Development of a pediatric multiple organ dysfunction score: use of two strategies.Medical Decision Making,1999, 19:399-410.
10Leteurtre S, Martinot A, Duhamel A, et al. Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective,observational, muhicentre study. Lancet, 2003,362 : 192-197.