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特殊药源性中性粒细胞缺乏症和急性中性粒细胞减少 被引量:3

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摘要 中性粒细胞缺乏是指外周血中性粒细胞计数<0.5×109/L,70%以上的病例由药物引起,常见致病药物几乎涉及所有种类.临床表现以明显咽干、发热、肺炎、败血症常见.患者易并发严重感染而危及生命,约2/3的患者并发败血症和感染性休克.然而通过早期发现和广谱抗生素及粒细胞集落刺激因子(G-CSF)的应用,目前总体死亡率在5%以下.在我国尚缺乏相关统计资料,但随着人口老龄化加重、抗生素及非甾体抗炎药物的过度使用,临床工作者对本病应提高警惕,力争早期发现和及时治疗.
出处 《国际输血及血液学杂志》 CAS 2010年第5期418-421,共4页 International Journal of Blood Transfusion and Hematology
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